ECT2 and cancer: Ect2 has been shown to be overexpressed in multiple cancers and associated with poor survival (Saito et al., 2004; Justilien and Fields, 2009; Fields and Justilien, 2010; Iyoda et al., 2010; Huff et al., 2013; Wang et al., 2016, 2018; Guo et al., 2017; Bai et al., 2018) (Table 1).