CDH17 and posterior cortical atrophy: Furthermore, MF such as cell cycle, apoptosis, DNA integrity checkpoint, cell adhesion, cadherin binding, and actin-binding which are known to affect the transition of androgen dependent to androgen-independent stages were seen to be dysregulated by our identified DEPs, hence depicting the involvement and contribution of protein markers in tumorigenesis and further vouching for their potential as biomarkers for PCa prognosis and diagnosis.