Based on common protein analysis, we found that there were 26 proteins that were differentially regulated significantly in both androgen dependent and androgen independent stages of cancer viz., TERA, TKT, GAPDH, HNRPD, HSPA4, PURB, GOT1, PSMA7, CS, UBA3, ALDOC, GNS, ECHB, ALB, 6PGD, HNRNPH3, STRAP, SPTAN1, FAH, LA, YWHAB, TAGLN2, HNRNPA2B1, LASP1, KTN1, and FKBP4 (Figure 1C). The gene discussed is PGD; the disease is cancer.