Agreeably, time kinetics of mRNA (Supplementary ) and protein (Figure 3(a)) levels of Nrf2 transcriptional targets (HO-1, NQO1, and SOD1) post RV-SA11 infection also revealed a trend similar to that of Nrf2: time-dependent gradual decrease beyond an initial induction (except SOD1 which did not show initial induction). The gene discussed is SOD1; the disease is infection.