Additionally, after reanalyzing the sequencing results of relevant research [37], we found that HO-1 increased significantly in the AP mouse model induced by caerulein (3.38-fold change vs. normal, p = 0.0001), while other related genes including Keap1, NQO1, and GCLM had no significant changes. This evidence concerns the gene GCLM and alkaline phosphatase measurement.