AFP and neoplasm: Other independent risk factors for DSS were ECOG performance score (HR 2.72, 95 percent CI 1.35–5.40, P=0.004), AFP level ≥ 400 μg/L (HR 3.16, 95 percent CI 1.02–9.81), tumor size ≥ 10 cm (HR 2.20, 95 percent CI 1.02–4.74), and PVTT status (HR 3.13, 95 percent CI 1.52–6.41, P=0.002) (Figure 3).