Recent researches demonstrated implications of KIF1A, KIF5A, KIF12, KIF14, KIFC1 and KIFC3 in resistance to docetaxel by destabilizing microtubule [23–26], while KIF5A, KIF5B, KIF12, KIF20A and KIFC3 were found to reduce the efficacy of paclitaxel by inducing abnormal breakdown of microtubules in breast cancer treatment [24, 27–29]. The gene discussed is KIFC1; the disease is breast cancer.