CENPE and neoplasm: All 6 KIFs selected by LASSO regression were seen overexpressed in tumor samples comparing to normal samples (KIF10, KIF15, KIF18B, KIF4A: P < 0.0001; KIF18A: P = 0.0003; KIF20A: P = 0.0022), which in accordance with bioinformatics results (Fig. 4a).