Compared with CON lambs, relative P53, Fas, Bax, caspase-3, cytochrome C, TNF-α, NF-κB p65, and NF-κB pp65 protein levels were higher (P < 0.05) in livers from IUGR lambs, whereas those in livers from Arg- or NCG-treated IUGR lambs were lower than those from IUGR lambs (P < 0.05). Here, TP53 is linked to fetal growth restriction.