FHL1 and age-related macular degeneration: In line with this, we have shown that the AMD-associated minor allele of the single nucleotide polymorphism (SNP) rs1061170 (CFH-H402) within SCR7 impairs binding of CFH and FHL-1 to MDA-epitopes and its derivatives, malondialdehyde-acetaldehyde (MAA)-epitopes, present in the retina of AMD patients (14).