In a panel of 60 diverse human cancer cell lines (NCI-60) used by the Developmental Therapeutics Program of the US National Cancer Institute, we also found that both APOA1 (Fig. 2a) and APOE (Fig. 2b) mRNA levels were low [21, 22], with the exception, for apoE only, of the T-47D cell line and melanoma cell lines. This evidence concerns the gene APOE and cancer.