The effect of hyperoxia exposure on Ang1 expression persisted even in the presence of the miR-451 inhibitor; however, Ang1 expression in miR-451 inhibitor treated BPD mice was significantly higher compared to WT BPD mice and not statistically different to Ang1 expression in the WT RA group (Fig. 7c and e). This evidence concerns the gene ANGPT1 and bronchopulmonary dysplasia.