This rise in miR-451 expression in response to hyperoxia coincides with the decrease in MIF expression previously reported by our group using the same experimental model of hyperoxia induced BPD [12] and is consistent with published findings that miR-451 is one of several miRNAs differentially regulated in a murine model of hyperoxia-induced BPD [39]. The gene discussed is MIF; the disease is bronchopulmonary dysplasia.