A more recent study by Nguyen et al. with unselected patients with ST-elevation myocardial infarction treated by PCI and were all patient receive only 1000 mL of physiological saline given at a rate of 0.6 mL/kg per hour for 24 h except in those patients in Killip class III or IV; plasmatic NGAL did not provide additional value regarding CIN prediction compared with other risk [37]. The gene discussed is LCN2; the disease is ST Elevation Myocardial Infarction.