The results indicated that the silence of RGS16 expression suppressed the migration ability of glioma cell lines (Figure 7D,E,F, and G), Besides, the clonogenic assay showed that the proliferative capacity and clonogenicity of glioma cell lines were inhibited after transfection with RGS16 siRNA (Figure 7H,I). This evidence concerns the gene RGS16 and central nervous system cancer.