BCL2 and cancer: Bax, which is pro‐apoptotic and the anti‐apoptotic Bcl‐2, regulates intrinsic apoptosis senses of death signals.24 Previous studies have reported that the balance establishes the onset of apoptosis in mitochondria, and a high Bax/Bcl‐2 ratio is thought to promote apoptosis.25 Caspases‐3 and ‐9 act as executioners in apoptosis, and once they are activated, cleavage of their precursor forms occurs.26 PARP is the target protein of caspase‐3, affecting the repair of cancer cells.