Matrix metalloproteinases (MMPs) play a vital role in tumour migration and invasion by degradation of extracellular matrix.22 Hence, we assessed the expression of these key proteins associated with cell migration and invasion, including MMP‐9 and MMP‐2, and found that DHL significantly impeded the expressions of MMP‐2 and MMP‐9 (Figure 2C). This evidence concerns the gene MMP9 and neoplasm.