Expression and function of PTEN in human malignant tumour tissues and tumour cell lines can exert tumour inhibition through a variety of ways, the most important of which is to inhibit the PI3K/Akt pathway, in which PTEN has the role of ‘molecular switch’.36, 37 Bad protein is a typical Akt‐phosphorylated protein involved in cellular proliferation and apoptosis.38 Therefore, we were interested in the involvement of DHL in Akt signalling. This evidence concerns the gene PTEN and neoplasm.