BCL2L1 and laryngeal carcinoma: Particularly, Akt phosphorylates it at Ser136,47 after which, Bad attaches 14‐3‐3 protein subtypes and remains isolated in the cytoplasm, unknot able to bind Bcl‐2 or Bcl‐xL.48 Thus, Bad is deemed to be the intersection of pro‐apoptotic and anti‐apoptotic regulatory cascades, and the Akt/PI3K pathway is directly linked to the apoptotic mechanism.49 We observed that DHL treatment down‐regulated the phosphorylation level of Akt accompanied by decreasing the phosphorylation of Bad in laryngeal carcinoma in vivo as well as in vitro.