BMP4 and congestive heart failure: In this study we have found that: (a) the BMP4 expression in the heart of the transgenic mouse model of chronic heart failure (Tgαq*4 mice) was about 490% higher than in the heart of the healthy (WT) mice, (b) the spontaneous physical activity of 8 weeks did not affect the BMP4 expression in the heart muscle of the Tgαq*4 mice nor in the WT mice, (c) the performed physical activity decreased the BMP4 content in bone (tibiae) (~43%), but only in the group of Tgαq*44 mice, with no significant effect on the mineral part of bones.