It has also been demonstrated that among BMP family, BMP4 through upregulation of the calcineurin/nuclear‐factor of activated T‐cells (calcineurin/NFAT) pathway (Shahid et al., 2016) promotes cardiac fibrosis and is involved in pathological cardiac hypertrophy (Sun et al., 2013), which is a leading cause of heart failure. Here, BMP4 is linked to heart failure.