The [TIMP-2] × [IGFBP7] product is known to be a biomarker of kidney stress in multiple settings [18], while PCT is recognized as a suitable marker for sepsis (or infection) diagnosis and has recently been associated with AKI (contrast-induced AKI [19] and pancreatitis-associated AKI [20] and critically ill patients [7]). The gene discussed is TIMP2; the disease is infection.