Patients with the G2019S mutation, the most common mutation in LRRK2-PD, are clinically indistinguishable from idiopathic PD and most cases present similar pathological findings with degeneration of dopaminergic neurons in the substantia nigra and occurrence of Lewy-type α-synuclein pathology [3]. The gene discussed is LRRK2; the disease is Parkinson disease.