BCHE and Cognitive impairment: A set of allopathic medicine such as dopaminergic medications for PD and related motor disorders (Mizuno, 2014); cholinesterase inhibitors for treating cognitive disorders (Doody et al., 2009); analgesic drugs for pain (Chaudhuri and Schapira, 2009); anti-inflammatory (Tizabi et al., 2014) and antipsychotic drugs for dementia and other behavioral dysfunctions (Desai and Grossberg, 2005) are used to stop the tremor and refractory movement disorders (Okun, 2014).