ZEB1 and cancer: From a metabolic point of view, ZEB1 has been recently described to be a central component of adipogenesis (119) in non-cancer cell studies but ZEB1/2 have been more extensively studied in the context of cancer cell metabolism and appear to affect glycolysis (120) (Figure 1), to be affected by TCA cycle byproducts and drive EMT (121) (Figure 2), and to divert glycosphingolipid metabolism (122) (Figure 3).