The majority of SNHGs (SNHG1, SNHG12, SNHG20, SNHG15, SNHG16, SNHG3, SNHG5, SNHG6, SNHG7) function by sponging tumor- suppressing microRNAs, allowing the oncogene transcripts to be expressed. The gene discussed is SNHG20; the disease is neoplasm.