In recent years, studies have revealed that ZNF143 not only exists in most cancer cells but is also necessary for the normal development of tissues (Izumi et al., 2011; Halbig et al., 2012; Kawatsu et al., 2014; Paek et al., 2014; Wei et al., 2016; Paek et al., 2017). Here, ZNF143 is linked to cancer.