In adult sepsis, genes TDRD9, GPR84, and CD177 interacted via overlapped genes EXOSC4 (TDRD9 ↔ GPR84 ↔ CD177), ZDHHC19 (TDRD9 ↔ CD177) and NECAB1 (GPR84 ↔ CD177). Here, TDRD9 is linked to Sepsis.