The adult sepsis group exhibited indirect interaction between the CD177, GPR84, and TDRD9 hubs whereas the pediatric sepsis group exhibited indirect interaction between CD177, GPR84 and TDRD9; direct interaction between the GPR84 and TDRD9 hubs, indirect interaction between TDRD9 and the FGF13 and PCOLCE2 hubs and also between the PCOLCE2 and SLC16A3 hubs. This evidence concerns the gene PCOLCE2 and Sepsis.