Gene entities shared between sepsis and severe sepsis response hubs are; TDRD9 – LIN7A, GPR84 – ENTPD7, PYCT1A and ZDHHC19, CD177 – DDAH2 and RGL4, SLC16A3 – DENND3 and MBD6, MYL9 – CMTM5, ITGB3, ITGA2B, NRGN, SELP and TREML1. The gene discussed is TREML1; the disease is Sepsis.