Additionally, compared with RvD1 treatment, the administration of Boc-1 in vivo led to pathological changes (widespread protein cast, tubular necrosis and inflammatory cell infiltration; Figure 7A), increased in ATN scores (Figure 7B), renal dysfunction (manifested as high levels of Scr; Figure 7C) and inflammatory cytokines infiltration (high serum levels of IFN-γ, IL-6 and TNF-α; Figure 7F). This evidence concerns the gene IL6 and oculocutaneous albinism type 1.