IL-17 is an important inflammatory factor and its over-expression indicates a poorer treatment effect and prognosis for ischemic stroke (He et al., 2019; Tian et al., 2019; Zhou et al., 2019), which always abolishes some neuroprotective effect (Sun et al., 2018; Ma et al., 2018; Zhao et al., 2019). The gene discussed is IL17A; the disease is ischemic stroke.