In this study, the protein expression of IL-17 was downregulated by either giving As IV or knocking out IL-17 (Figure 6A), while the protein expression of Wnt2 and Nestin in the ipsilateral hippocampus was upregulated by knocking out IL-17 after stroke in vivo, by western blotting (Figures 6B, C). The gene discussed is NES; the disease is Stroke.