IFNG and myeloid sarcoma: The detection of IFN-γ in astrocytes of active chronic MS plaques and its ability to induce class II major histocompatibility antigen HLA-DR-Ia in astrocytes in vivo suggested that IFN-γ may play an important role in the development of MS lesions (Traugott and Lebon, 1988; Hashioka et al., 2009).