For this purpose, we studied possible changes in the TH1 (IL2), TH2 (IL-4), Th17 (IL-17) and Treg (Foxp3) phenotypes by analyzing changes in the expression of their markers in eight cell lines: MOLT-14, RPMI-8402, SU-DHL-1, L-82, HPB-ALL, HUT-78, JURKAT and HH. The gene discussed is IL2; the disease is acute lymphoblastic leukemia.