The vast majority are characterized by TP53 mutations and lack mutations of KRAS, BRAF or ERBB2. Low-grade serous ovarian carcinoma (LGSOC) accounts for less than 5% of all ovarian serous carcinomas, other epithelial ovarian cancer types are endometrioid (8–10%), clear cell (8%), seromucinous (3%), mucinous (3%) and Brenner (1%) tumors3. The gene discussed is ERBB2; the disease is ovarian serous carcinoma.