We examined the expression of CD25, CD45RA, CD127, CD49d, CD161, CD152, and Helios as well as cytokines, including IL-2, IL-17, and IFN-γ, on gated CD4+Foxp3+ T cells in active SLE patients and healthy controls (Fig. 4). This evidence concerns the gene KLRB1 and systemic lupus erythematosus.