Infiltration of the tumor stroma by T-regulatory FOXP3+ cells showed a significantly negative low correlation to CRP (Spearman’s rho –0.18, 95% CI from –0.32 to –0.05 for all non-irradiated and –0.24, 95% CI from –0.42 to –0.05 for non-irradiated rectal cancers (Table 3). This evidence concerns the gene FOXP3 and rectal cancer.