MET and medullary thyroid gland carcinoma: Cabozantinib is a tyrosine kinase inhibitor (TKI) that targets tyrosine kinases, such as vascular endothelial growth factor receptor (VEGFR) and hepatocyte growth factor receptor (MET) and it has already been approved as a first-line treatment for advanced medullary thyroid carcinomas and advanced renal cell carcinomas (RCC).