A study on the association between XRCC3 polymorphisms and bladder carcinoma examined the effect of XRCC3 haplotypes composed of the polymorphisms (rs86153, rs861531, rs861537, rs861534, and rs1799794) on bladder cancer development, and the T-A haplotype with a T allele on rs861531 and an A allele on rs861537 showed protective effects for bladder cancer [29]. The gene discussed is XRCC3; the disease is urinary bladder carcinoma.