The ERBB family of tyrosine kinase receptors, including EGFR (ERBB1/HER1), ERBB2 (Neu/HER2), ERBB3 (HER3), and ERBB4 (or HER4), has largely been associated with cancer pathogenesis and epithelium-mesenchymal transition (EMT) [15]. The gene discussed is ERBB2; the disease is cancer.