TP63 and PTHLH genes seem to deserve special interest, since their expression correlates positively and negatively with ERBB4 in medulloblastoma cells and samples, respectively, and their expression is related to patient prognosis, following the same pattern as ERBB4. TP63 is an important transcriptor factorthat belongs to the TP53 family, and is a key developmental and stem cell factor with diverse and complex functions in tumorigenesis. Here, ERBB4 is linked to medulloblastoma.