IDH2 and central nervous system cancer: As for the prognostic value of these results, by performing a univariate Cox regression analysis on the expression levels in the CGGA dataset, these authors found that eleven out of thirteen tested genes were significantly correlated with OS, with in particular FTO behaving always as a protective gene in all types of glioma, including low-grade gliomas and glioblastomas, both IDH wild-type and IDH mutant.