SIRT1 and metabolic syndrome: In addition to SIRT1, resveratrol may act through other mechanisms to ameliorate the symptoms of metabolic syndrome and related disorders, such as AMP-activated protein kinase (AMPK), Nuclear factor (erythroid-derived 2)-like 2 (Nrf2), Renin-Angiotensin System, and the nuclear factor kappa-B cells (NF-κB) family of proteins [15].