Luminal A (estrogen receptor, ER+ and/or progesterone receptor, PR+/− and Human Epidermal Growth Factor Receptor 2, HER2−; low Ki67 <14%), Luminal B (ER+ and/or PR+/−, HER2− with Ki67 ≥14% as well as ER+ and/or PR+/−, HER2+ with any Ki67), HER2 (ER−, PR−, and HER2+ with any Ki67) and Triple Negative Breast Cancer (TNBC, ER−, PR−, HER2− with any Ki67). The gene discussed is PGR; the disease is triple-negative breast carcinoma.