Recently, it has been shown that differentiating vacuolar myopathy due to LAMP2 variants from other types of vacuolar myopathy can be facilitated by application of p62, microtubule-associated protein 1A/1B-light chain 3 (LC-3), and LAMP2 staining [80]. The gene discussed is LAMP2; the disease is X-linked myopathy with excessive autophagy.