PDGFB and neoplasm: Lately, Falcon et al. [71] found that inhibition of PDGF-B signaling in Lewis lung carcinomas by the DNA aptamer AX102 enhanced the transport and effectiveness of the chemotherapeutic drug cyclophosphamide by augmenting the efficiency of tumor blood vessels; combined application of cyclophosphamide and AX102 also showed synergistic effects on tumor cell proliferation in RIP-Tag2 tumors.