This is shown by the observance that adenocarcinoma is commonly caused by liver kinase B1 (STK11) mutations, epidermal growth factor receptor (EGFR) kinase domain mutations, tyrosine-protein kinase MET (MET) amplification, Kirsten rat sarcoma viral (KRAS) mutations, and anaplastic lymphoma kinase (ALK) mutations. This evidence concerns the gene STK11 and adenocarcinoma.