Out of these, 624 genes (e.g., CKMT1A/B, CITED1, PPARGC1A/B, and CPT1B) were lower expressed in those adipocytes that carried the obesity-risk genotype and the enriched pathways (maintained by the normal T/T genotype) included fatty acid metabolism, thermogenesis, respiratory electron transport, and the signaling by retinoic acid (which showed DN specific appearance as well). This evidence concerns the gene PPARGC1A and Obesity.