BACE1 and Alzheimer disease: The major findings were (i) MNCM extract was rich in anthocyanins and anthocyanidins, especially cyanidin, kuromanin, and keracyanin, which are probably involved in antioxidative stress; (ii) MNCM extract exhibited up to 50% inhibitory activity against AChE, BChE, and BACE-1; (iii) MNCM extract protected neuronal cells from H2O2 or Aβ peptide-induced toxicity and promoted neurite outgrowth; and (iv) MNCM extract reduced Aβ1-42 peptides by inhibiting BACE-1 activity in a Drosophila model of AD.