While the toxic injury in the CCl4 model was unaffected according to histology or ALT levels, liver fibrosis was markedly reduced upon GPR84 or ASK1 inhibition, based on Sirius-Red-staining (* p = 0.084 upon GPR84 treatment) and hepatic hydroxyproline content (Figure 6B–C). This evidence concerns the gene GPT and Hepatic fibrosis.