ATG7 and myocardial infarction: For example, Wang et al. revealed that the a long noncoding RNA, named autophagy promoting factor (APF) promotes autophagy and myocardial infarction by targeting miR-188-3p, they proved that the inhibition of miR-188-3p expression increased the expression of ATG7, which leading to increased myocardial infarction sizes in response to ischemia/reperfusion injury in vivo [36].