Platelets present granules with Interleukin 8 (IL-8) which is a potent neutrophil chemoattractant [7] and its cytoplasm contains P-selectin that induces overproduction of superoxide and the formation of neutrophil-platelet aggregates, which are elevated in patients with UC and related with the activity also in Dextran Sulfate Sodium (DSS)-Induced Colitis Model the inhibition of this aggregates suppress the appearance of colon inflammation [8,9]. This evidence concerns the gene CXCL8 and colitis.