The large majority of neurofibroma targets (60 of 71; 85%) were also associated with HuR in the MPNST samples, whereas 216 HuR-bound transcripts were exclusively expressed in MPNST samples (Figure 2A), in line with the high HuR expression in MPNST samples, and supporting a role for HuR in malignant Schwann cell tumors. This evidence concerns the gene ELAVL1 and malignant peripheral nerve sheath tumor.