NF1 and malignant peripheral nerve sheath tumor: Three of the cell lines (ST88-14, 90-8, and S462) were derived from NF1 patients with confirmed loss of heterozygosity at the NF1 locus for all 3 cell lines; the 90-8 cell line additionally showed a known microdeletion of NF1, whereas the sporadic MPNST line STS-26T had no mutations detected in the 60 exons of the NF1 gene.