After integrating the 133 miR-31-5p target genes with the 1,556 DEGs in COAD, we identified 8 specific genes (SLC6A6, SATB2, TNS1, KRT80, FGF7, CACNB2, MAP1B, and DMD) that might be targeted by miR-31-5p and play a role in COAD progression (Figure 2E). This evidence concerns the gene KRT80 and colon adenocarcinoma.