PPP3CA and urinary bladder carcinoma: It is worth noting that the endogenous threonine 44‐phosphorylated form of C16orf74 interacted with the protein phosphatase 3 catalytic subunit alpha (PPP3CA) in the PPP3CA‐binding motif in PDAC cells, and the overexpression of mutants of C16orf74 lacking the PDIIIT sequence repressed the invasive activity relative to wild‐type C16orf74, implying that this link was indispensable for PDAC cell invasion18 C16orf74 has been found to be positively correlated with PRSS3 in bladder cancer, and this relationship might act as an instrumental role in promoting its invasiveness.17