Several responsible genes whose malfunction induces craniofacial malformations have been identified and are conserved between human and zebrafish, including Tcof1 and Polr1 (Treacher Collins syndrome), Chd7 (CHARGE syndrome), Sox9 (Pierre Robin sequence), Tfap2a (Branchio‐Oculo‐Facial syndrome), and Sox10 (Waardenburg syndrome).28, 29, 30, 31, 32, 33. This evidence concerns the gene SOX9 and branchiooculofacial syndrome.