A common amplicon has been detected during the conversion to androgen-independent prostate cancer in a short region spanning chromosome 8q which also contains the c-Myc oncogene, and in more than 70% of clinical androgen-independent prostate tumor samples, amplification of the c-Myc gene has been found by fluorescence in situ hybridization11,12. This evidence concerns the gene MYC and prostate neoplasm.