Because the AKT-mTOR-HIF1α pathway is an essential pathway that governs glycolysis and proliferation in CRC and FDFT1 expression is inversely correlated with mTOR expression, we decided to determine whether FDFT1 is negatively correlated with the AKT-mTOR-HIF1α pathway. The gene discussed is AKT1; the disease is colorectal carcinoma.