GNAQ and neoplasm: A small RNAi screen in three cell lines, directed against a list of genes selected based on gain candidates, in a cell line derived from the UM22 tumor demonstrated that a majority of siRNA pools negatively affected proliferation (cell count) or viability (ATP production) to a similar or higher level than an siRNA against GNAQ (Fig. 2h, Supplementary Fig. 3c, d, Supplementary Data 3).