To explore the regulatory mechanism of Drp1 in metabolic disorders after ischemic injury in vascular tissues, we extracted SMAs from Drp1 KO mice for metabonomic analysis to determine the metabolic molecules and pathways related to Drp1 both under normal and ischemic conditions (Figs. 7F and S4A–D, Table 2). The gene discussed is DNM1L; the disease is Other metabolic disease.